ZOVIRAX Cream: Approved By 
The FDA Nearly A Decade Ago.
Like many medicines, acyclovir treats more than one medical condition. When ZOVIRAX was first approved by the FDA over 25 years ago, it was marketed in intravenous form administered at a hospital, or as ZOVIRAX Ointment, as treatment for the initial outbreak of HSV-2 of genital herpes.

Over the years—and with more clinical studies—ZOVIRAX® (acyclovir) Cream 5% was approved by the FDA to treat HSV-1, or recurrent cold sores.

Acyclovir: One Of The First Antiviral Medicines Ever Discovered

The active ingredient found in ZOVIRAX Ointment and ZOVIRAX Cream is acyclovir. Discovered in the 1970s, acyclovir was an important medical breakthrough and is still used today.


After many major medical contributions, including the discovery of acyclovir, Dr. Gertrude Elion was awarded the highest possible honor for a scientist—the President's National Medal of Science—which she received years later.


So with ZOVIRAX Cream, you can feel confident that you're using a treatment that has been rigorously tested and covered by many health insurance plans. In fact 90% of the top 45 insurance plans reimburse patients for ZOVIRAX topicals.